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Combined Use of a Solid-Phase Hexapeptide Ligand Library with Liquid Chromatography and Two-Dimensional Difference Gel Electrophoresis for Intact Plasma Proteomics

The intact plasma proteome is of great interest in biomarker studies because intact proteins reflect posttranslational protein processing such as phosphorylation that may correspond to disease status. We examined the utility of a solid-phase hexapeptide ligand library in combination with conventiona...

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Detalles Bibliográficos
Autores principales: Hagiwara, Tatsuo, Saito, Yumi, Nakamura, Yukiko, Tomonaga, Takeshi, Murakami, Yasufumi, Kondo, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282153/
https://www.ncbi.nlm.nih.gov/pubmed/22389768
http://dx.doi.org/10.1155/2011/739615