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Inhibition of Inducible Nitric Oxide Synthase Attenuates Monosodium Urate-induced Inflammation in Mice

The present study elucidated the effect of the selective inducible nitric oxide synthase (iNOS) inhibitor N(6)-(1-iminoethyl)-L-lysine (L-NIL) on monosodium urate (MSU) crystal-induced inflammation and edema in mice feet. L-NIL (5 or 10 mg/kg/day) was administered intraperitoneally 4 h before inject...

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Detalles Bibliográficos
Autores principales: Ju, Tae-Jin, Dan, Jin-Myoung, Cho, Young-Je, Park, So-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282224/
https://www.ncbi.nlm.nih.gov/pubmed/22359474
http://dx.doi.org/10.4196/kjpp.2011.15.6.363