Cytotoxicities and Quantitative Structure Activity Relationships of B13 Sulfonamides in HT-29 and A549 Cells

B13 analogues are being considered as therapeutic agents for cancer cells, since B13 is a ceramide analogue and inhibits ceramidase to promote apoptosis in cancer cells. B13 sulfonamides are assumed to have biological activity similar to B13, since they are made by bioisosterically substituting the...

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Detalles Bibliográficos
Autores principales: Lee, Seul Ki Chan, Park, Sang Min, Im, Chaeuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282231/
https://www.ncbi.nlm.nih.gov/pubmed/22359481
http://dx.doi.org/10.4196/kjpp.2011.15.6.423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282231/
https://www.ncbi.nlm.nih.gov/pubmed/22359481
http://dx.doi.org/10.4196/kjpp.2011.15.6.423

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