Homology modeling, active site prediction, and targeting the anti hypertension activity through molecular docking on endothelin – B receptor domain

In cardiovascular system, activation of Endothelin receptors causes vasoconstriction which leads to Pulmonary Arterial Hypertension (PAH). Endothelin receptor antagonism has emerged as an important therapeutic strategy in pulmonary arterial hypertension. Bosentan is intended to affect vasoconstricti...

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Detalles Bibliográficos
Autores principales: Rayalu, Daddam Jayasimha, Selvaraj, Chandrabose, Singh, Sanjeev Kumar, Ganeshan, Ramakrishan, Kumar, Nagapatla Udaya, Seshapani, Panthangi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282261/
https://www.ncbi.nlm.nih.gov/pubmed/22359440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282261/
https://www.ncbi.nlm.nih.gov/pubmed/22359440

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