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Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection

The inflammatory response to lung infections must be tightly regulated, enabling pathogen elimination while maintaining crucial gas exchange. Using recently described “depletion of regulatory T cell” (DEREG) mice, we found that selective depletion of regulatory T cells (Tregs) during acute respirato...

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Detalles Bibliográficos
Autores principales: Loebbermann, J, Thornton, H, Durant, L, Sparwasser, T, Webster, K E, Sprent, J, Culley, F J, Johansson, C, Openshaw, P J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282434/
https://www.ncbi.nlm.nih.gov/pubmed/22236998
http://dx.doi.org/10.1038/mi.2011.62