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Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection
The inflammatory response to lung infections must be tightly regulated, enabling pathogen elimination while maintaining crucial gas exchange. Using recently described “depletion of regulatory T cell” (DEREG) mice, we found that selective depletion of regulatory T cells (Tregs) during acute respirato...
Autores principales: | Loebbermann, J, Thornton, H, Durant, L, Sparwasser, T, Webster, K E, Sprent, J, Culley, F J, Johansson, C, Openshaw, P J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282434/ https://www.ncbi.nlm.nih.gov/pubmed/22236998 http://dx.doi.org/10.1038/mi.2011.62 |
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