Small Molecule Inhibition of RISC Loading

[Image: see text] Argonaute proteins are the core components of the microRNP/RISC. The biogenesis and function of microRNAs and endo- and exo- siRNAs are regulated by Ago2, an Argonaute protein with RNA binding and nuclease activities. Currently, there are no in vitro assays suitable for large-scale...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Grace S., Chiu, Chun-Hao, Garchow, Barry G., Metzler, David, Diamond, Scott L., Kiriakidou, Marianthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282558/
https://www.ncbi.nlm.nih.gov/pubmed/22026461
http://dx.doi.org/10.1021/cb200253h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282558/
https://www.ncbi.nlm.nih.gov/pubmed/22026461
http://dx.doi.org/10.1021/cb200253h

Ejemplares similares