Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation

The objective of our investigation was to design a self-microemulsifying drug-delivery system (SMEDDS) to improve the bioavailability of probucol. SMEDDS was composed of probucol, olive oil, Lauroglycol FCC, Cremophor EL, Tween-80, and PEG-400. Droplet sizes were determined. In vitro release was inv...

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Detalles Bibliográficos
Autores principales: Sha, Xianyi, Wu, Juan, Chen, Yanzuo, Fang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282610/
https://www.ncbi.nlm.nih.gov/pubmed/22359449
http://dx.doi.org/10.2147/IJN.S28052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282610/
https://www.ncbi.nlm.nih.gov/pubmed/22359449
http://dx.doi.org/10.2147/IJN.S28052

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