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Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation

The objective of our investigation was to design a self-microemulsifying drug-delivery system (SMEDDS) to improve the bioavailability of probucol. SMEDDS was composed of probucol, olive oil, Lauroglycol FCC, Cremophor EL, Tween-80, and PEG-400. Droplet sizes were determined. In vitro release was inv...

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Detalles Bibliográficos
Autores principales:	Sha, Xianyi, Wu, Juan, Chen, Yanzuo, Fang, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282610/ https://www.ncbi.nlm.nih.gov/pubmed/22359449 http://dx.doi.org/10.2147/IJN.S28052

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