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Potent therapeutic activity of folate receptor-targeted liposomal carboplatin in the localized treatment of intraperitoneally grown human ovarian tumor xenograft

Intraperitoneal (IP) therapy with platinum (Pt)-based drugs has shown promising results clinically; however, high locoregional concentration of the drug could lead to adverse side effects. In this study, IP administration was coupled with a folate receptor-targeted (FRT) liposomal system, in an atte...

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Detalles Bibliográficos
Autores principales: Chaudhury, Anumita, Das, Surajit, Bunte, Ralph M, Chiu, Gigi NC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282613/
https://www.ncbi.nlm.nih.gov/pubmed/22359453
http://dx.doi.org/10.2147/IJN.S26172