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Potent therapeutic activity of folate receptor-targeted liposomal carboplatin in the localized treatment of intraperitoneally grown human ovarian tumor xenograft
Intraperitoneal (IP) therapy with platinum (Pt)-based drugs has shown promising results clinically; however, high locoregional concentration of the drug could lead to adverse side effects. In this study, IP administration was coupled with a folate receptor-targeted (FRT) liposomal system, in an atte...
Autores principales: | Chaudhury, Anumita, Das, Surajit, Bunte, Ralph M, Chiu, Gigi NC |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282613/ https://www.ncbi.nlm.nih.gov/pubmed/22359453 http://dx.doi.org/10.2147/IJN.S26172 |
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