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Novel biodegradable sandwich-structured nanofibrous drug-eluting membranes for repair of infected wounds: an in vitro and in vivo study

BACKGROUND: The purpose of this study was to develop novel sandwich-structured nanofibrous membranes to provide sustained-release delivery of vancomycin, gentamicin, and lidocaine for repair of infected wounds. METHODS: To prepare the biodegradable membranes, poly(D, L)-lactide-co-glycolide (PLGA),...

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Detalles Bibliográficos
Autores principales: Chen, Dave Wei-Chih, Liao, Jun-Yi, Liu, Shih-Jung, Chan, Err-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282614/
https://www.ncbi.nlm.nih.gov/pubmed/22359454
http://dx.doi.org/10.2147/IJN.S29119