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A common variant of the MACC1 gene is significantly associated with overall survival in colorectal cancer patients

BACKGROUND: The newly discovered metastasis-associated in colon cancer-1 (MACC1) gene is a key regulator of the HGF/MET pathway. Deregulation of HGF/MET signaling is reported as a prognostic marker for tumorigenesis, early stage invasion, and metastasis. High expression levels of MACC1 have been ass...

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Detalles Bibliográficos
Autores principales: Lang, Alois H, Geller-Rhomberg, Simone, Winder, Thomas, Stark, Nicole, Gasser, Klaus, Hartmann, Bernd, Kohler, Bertram, Grizelj, Ina, Drexel, Heinz, Muendlein, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282635/
https://www.ncbi.nlm.nih.gov/pubmed/22251819
http://dx.doi.org/10.1186/1471-2407-12-20