Cargando…
siRNA against presenilin 1 (PS1) down regulates amyloid β42 production in IMR-32 cells
BACKGROUND: One of the pathological hallmarks of Alzheimer's disease (AD) is the deposition of the ~4 kDa amyloid β protein (Aβ) within lesions known as senile plaques. Aβ is also deposited in the walls of cerebral blood vessels in many cases of AD. A substantial proportion of the Aβ that accum...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282656/ https://www.ncbi.nlm.nih.gov/pubmed/22214483 http://dx.doi.org/10.1186/1423-0127-19-2 |