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S. pombe Kinesins-8 Promote Both Nucleation and Catastrophe of Microtubules

The kinesins-8 were originally thought to be microtubule depolymerases, but are now emerging as more versatile catalysts of microtubule dynamics. We show here that S. pombe Klp5-436 and Klp6-440 are non-processive plus-end-directed motors whose in vitro velocities on S. pombe microtubules at 7 and 2...

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Detalles Bibliográficos
Autores principales: Erent, Muriel, Drummond, Douglas R., Cross, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282699/
https://www.ncbi.nlm.nih.gov/pubmed/22363481
http://dx.doi.org/10.1371/journal.pone.0030738