Novel Protein Kinase Signaling Systems Regulating Lifespan Identified by Small Molecule Library Screening Using Drosophila

Protein kinase signaling cascades control most aspects of cellular function. The ATP binding domains of signaling protein kinases are the targets of most available inhibitors. These domains are highly conserved from mammals to flies. Herein we describe screening of a library of small molecule inhibi...

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Detalles Bibliográficos
Autores principales: Spindler, Stephen R., Li, Rui, Dhahbi, Joseph M., Yamakawa, Amy, Sauer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282711/
https://www.ncbi.nlm.nih.gov/pubmed/22363408
http://dx.doi.org/10.1371/journal.pone.0029782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282711/
https://www.ncbi.nlm.nih.gov/pubmed/22363408
http://dx.doi.org/10.1371/journal.pone.0029782

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