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Severe Pandemic H1N1 2009 Infection Is Associated with Transient NK and T Deficiency and Aberrant CD8 Responses

BACKGROUND: It is unclear why the severity of influenza varies in healthy adults or why the burden of severe influenza shifts to young adults when pandemic strains emerge. One possibility is that cross-protective T cell responses wane in this age group in the absence of recent infection. We therefor...

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Detalles Bibliográficos
Autores principales: Fox, Annette, Hoa, Le Nguyen Minh, Horby, Peter, van Doorn, H. Rogier, Trung, Nguyen Vu, Ha, Nguyen Hong, Cap, Nguyen Trung, Phu, Vu Dinh, Ha, Nguyen Minh, Ngoc, Diep Nguyen Thi, Ngoc, Bich Vu Thi, Kieu, Huong Tran Thi, Taylor, Walter R., Farrar, Jeremy, Wertheim, Heiman, Kinh, Nguyen Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282732/
https://www.ncbi.nlm.nih.gov/pubmed/22363665
http://dx.doi.org/10.1371/journal.pone.0031535