Prolonged Exposure to a Mer Ligand in Leukemia: Gas6 Favors Expression of a Partial Mer Glycoform and Reveals a Novel Role for Mer in the Nucleus

Mer tyrosine kinase is ectopically expressed in acute lymphoblastic leukemia and associated with enhanced chemoresistance and disease progression. While such effects are generally ascribed to increased engagement of oncogenic pathways downstream of Mer stimulation by its ligand, Gas6, Mer has not be...

Descripción completa

Detalles Bibliográficos
Autores principales: Migdall-Wilson, Justine, Bates, Christine, Schlegel, Jennifer, Brandão, Luis, Linger, Rachel M. A., DeRyckere, Deborah, Graham, Douglas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282750/
https://www.ncbi.nlm.nih.gov/pubmed/22363695
http://dx.doi.org/10.1371/journal.pone.0031635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282750/
https://www.ncbi.nlm.nih.gov/pubmed/22363695
http://dx.doi.org/10.1371/journal.pone.0031635

Ejemplares similares