Identification of Mammalian Protein Quality Control Factors by High-Throughput Cellular Imaging

Protein Quality Control (PQC) pathways are essential to maintain the equilibrium between protein folding and the clearance of misfolded proteins. In order to discover novel human PQC factors, we developed a high-content, high-throughput cell-based assay to assess PQC activity. The assay is based on...

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Detalles Bibliográficos
Autores principales: Pegoraro, Gianluca, Voss, Ty C., Martin, Scott E., Tuzmen, Pinar, Guha, Rajarshi, Misteli, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282772/
https://www.ncbi.nlm.nih.gov/pubmed/22363705
http://dx.doi.org/10.1371/journal.pone.0031684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282772/
https://www.ncbi.nlm.nih.gov/pubmed/22363705
http://dx.doi.org/10.1371/journal.pone.0031684

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