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Identification of Mammalian Protein Quality Control Factors by High-Throughput Cellular Imaging
Protein Quality Control (PQC) pathways are essential to maintain the equilibrium between protein folding and the clearance of misfolded proteins. In order to discover novel human PQC factors, we developed a high-content, high-throughput cell-based assay to assess PQC activity. The assay is based on...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282772/ https://www.ncbi.nlm.nih.gov/pubmed/22363705 http://dx.doi.org/10.1371/journal.pone.0031684 |