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Lymphocyte Subsets Show Different Response Patterns to In Vivo Bound Natalizumab—A Flow Cytometric Study on Patients with Multiple Sclerosis

Natalizumab is an effective monoclonal antibody therapy for the treatment of relapsing- remitting multiple sclerosis (RRMS) and interferes with immune cell migration into the central nervous system by blocking the α(4) subunit of very-late activation antigen-4 (VLA-4). Although well tolerated and ve...

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Detalles Bibliográficos
Autores principales: Harrer, Andrea, Pilz, Georg, Einhaeupl, Max, Oppermann, Katrin, Hitzl, Wolfgang, Wipfler, Peter, Sellner, Johann, Golaszewski, Stefan, Afazel, Shahrzad, Haschke-Becher, Elisabeth, Trinka, Eugen, Kraus, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282779/
https://www.ncbi.nlm.nih.gov/pubmed/22363732
http://dx.doi.org/10.1371/journal.pone.0031784