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A Pivotal Role of Vitamin B9 in the Maintenance of Regulatory T Cells In Vitro and In Vivo

Dietary factors regulate immunological function, but the underlying mechanisms remain elusive. Here we show that vitamin B9 is a survival factor for regulatory T (Treg) cells expressing high levels of vitamin B9 receptor (folate receptor 4). In vitamin B9-reduced condition in vitro, Treg cells could...

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Detalles Bibliográficos
Autores principales: Kunisawa, Jun, Hashimoto, Eri, Ishikawa, Izumi, Kiyono, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282783/
https://www.ncbi.nlm.nih.gov/pubmed/22363800
http://dx.doi.org/10.1371/journal.pone.0032094