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Comparison of Phenotypes between Different vangl2 Mutants Demonstrates Dominant Effects of the Looptail Mutation during Hair Cell Development

Experiments utilizing the Looptail mutant mouse, which harbors a missense mutation in the vangl2 gene, have been essential for studies of planar polarity and linking the function of the core planar cell polarity proteins to other developmental signals. Originally described as having dominant phenoty...

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Detalles Bibliográficos
Autores principales: Yin, Haifeng, Copley, Catherine O., Goodrich, Lisa V., Deans, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282788/
https://www.ncbi.nlm.nih.gov/pubmed/22363783
http://dx.doi.org/10.1371/journal.pone.0031988