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Catalase Deficiency Accelerates Diabetic Renal Injury Through Peroxisomal Dysfunction

Mitochondrial reactive oxygen species (ROS) play an important role in diabetes complications, including diabetic nephropathy (DN). Plasma free fatty acids (FFAs) as well as glucose are increased in diabetes, and peroxisomes and mitochondria participate in FFA oxidation in an interconnected fashion....

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Detalles Bibliográficos
Autores principales: Hwang, Inah, Lee, Jiyoun, Huh, Joo Young, Park, Jehyun, Lee, Hi Bahl, Ho, Ye-Shih, Ha, Hunjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282807/
https://www.ncbi.nlm.nih.gov/pubmed/22315314
http://dx.doi.org/10.2337/db11-0584