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Thiazolidinedione Treatment Decreases Oxidative Stress in Spontaneously Hypertensive Heart Failure Rats Through Attenuation of Inducible Nitric Oxide Synthase–Mediated Lipid Radical Formation

The current study was designed to test the hypothesis that inducible nitric oxide synthase (iNOS)-mediated lipid free radical overproduction exists in an insulin-resistant rat model and that reducing the accumulation of toxic metabolites is associated with improved insulin signaling and metabolic re...

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Detalles Bibliográficos
Autores principales: Kadiiska, Maria B., Bonini, Marcelo G., Ruggiero, Christine, Cleland, Ellen, Wicks, Shawna, Stadler, Krisztian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282814/
https://www.ncbi.nlm.nih.gov/pubmed/22315311
http://dx.doi.org/10.2337/db11-1091