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Hepatic TRAF2 Regulates Glucose Metabolism Through Enhancing Glucagon Responses

Obesity is associated with intrahepatic inflammation that promotes insulin resistance and type 2 diabetes. Tumor necrosis factor receptor–associated factor (TRAF)2 is a key adaptor molecule that is known to mediate proinflammatory cytokine signaling in immune cells; however, its metabolic function r...

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Detalles Bibliográficos
Autores principales: Chen, Zheng, Sheng, Liang, Shen, Hong, Zhao, Yujun, Wang, Shaomeng, Brink, Robert, Rui, Liangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282816/
https://www.ncbi.nlm.nih.gov/pubmed/22315325
http://dx.doi.org/10.2337/db11-0474