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Hepatic TRAF2 Regulates Glucose Metabolism Through Enhancing Glucagon Responses
Obesity is associated with intrahepatic inflammation that promotes insulin resistance and type 2 diabetes. Tumor necrosis factor receptor–associated factor (TRAF)2 is a key adaptor molecule that is known to mediate proinflammatory cytokine signaling in immune cells; however, its metabolic function r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282816/ https://www.ncbi.nlm.nih.gov/pubmed/22315325 http://dx.doi.org/10.2337/db11-0474 |