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Improving gene expression data interpretation by finding latent factors that co-regulate gene modules with clinical factors
BACKGROUND: In the analysis of high-throughput data with a clinical outcome, researchers mostly focus on genes/proteins that show first-order relations with the clinical outcome. While this approach yields biomarkers and biological mechanisms that are easily interpretable, it may miss information th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282832/ https://www.ncbi.nlm.nih.gov/pubmed/22087761 http://dx.doi.org/10.1186/1471-2164-12-563 |