A53T-alpha-synuclein-overexpression in the mouse nigrostriatal pathway leads to early increase of 14-3-3 epsilon and late increase of GFAP

Parkinson’s disease (PD) is a neurodegenerative disorder frequent at old age characterized by atrophy of the nigrostriatal projection. Overexpression and A53T-mutation of the presynaptic, vesicle-associated chaperone alpha-synuclein are known to cause early-onset autosomal dominant PD. We previously...

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Detalles Bibliográficos
Autores principales: Kurz, Alexander, May, Caroline, Schmidt, Oliver, Müller, Thorsten, Stephan, Christian, Meyer, Helmut E., Gispert, Suzana, Auburger, Georg, Marcus, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Basic Neurosciences, Genetics and Immunology - Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282907/
https://www.ncbi.nlm.nih.gov/pubmed/21960009
http://dx.doi.org/10.1007/s00702-011-0717-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282907/
https://www.ncbi.nlm.nih.gov/pubmed/21960009
http://dx.doi.org/10.1007/s00702-011-0717-3

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