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Changes in transcriptional orientation are associated with increases in evolutionary rates of enterobacterial genes

BACKGROUND: Changes in transcriptional orientation (“CTOs”) occur frequently in prokaryotic genomes. Such changes usually result from genomic inversions, which may cause a conflict between the directions of replication and transcription and an increase in mutation rate. However, CTOs do not always l...

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Detalles Bibliográficos
Autores principales: Lin, Chieh-Hua, Lian, Chun-Yi, Hsiung, Chao Agnes, Chen, Feng-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283321/
https://www.ncbi.nlm.nih.gov/pubmed/22152004
http://dx.doi.org/10.1186/1471-2105-12-S9-S19