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Changes in transcriptional orientation are associated with increases in evolutionary rates of enterobacterial genes
BACKGROUND: Changes in transcriptional orientation (“CTOs”) occur frequently in prokaryotic genomes. Such changes usually result from genomic inversions, which may cause a conflict between the directions of replication and transcription and an increase in mutation rate. However, CTOs do not always l...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283321/ https://www.ncbi.nlm.nih.gov/pubmed/22152004 http://dx.doi.org/10.1186/1471-2105-12-S9-S19 |