Granulocyte-macrophage stimulating factor (GM-CSF) increases circulating dendritic cells but does not abrogate suppression of adaptive cellular immunity in patients with metastatic colorectal cancer receiving chemotherapy

BACKGROUND: Advanced cancer and chemotherapy are both associated with immune system suppression. We initiated a clinical trial in patients receiving chemotherapy for metastatic colorectal cancer to determine if administration of GM-CSF in this setting was immunostimulatory. METHODS: Between June, 20...

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Detalles Bibliográficos
Autores principales: Martinez, Micaela, Ono, Nadia, Planutiene, Marina, Planutis, Kestutis, Nelson, Edward L, Holcombe, Randall F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283445/
https://www.ncbi.nlm.nih.gov/pubmed/22270330
http://dx.doi.org/10.1186/1475-2867-12-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283445/
https://www.ncbi.nlm.nih.gov/pubmed/22270330
http://dx.doi.org/10.1186/1475-2867-12-2

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