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Granulocyte-macrophage stimulating factor (GM-CSF) increases circulating dendritic cells but does not abrogate suppression of adaptive cellular immunity in patients with metastatic colorectal cancer receiving chemotherapy
BACKGROUND: Advanced cancer and chemotherapy are both associated with immune system suppression. We initiated a clinical trial in patients receiving chemotherapy for metastatic colorectal cancer to determine if administration of GM-CSF in this setting was immunostimulatory. METHODS: Between June, 20...
Autores principales: | Martinez, Micaela, Ono, Nadia, Planutiene, Marina, Planutis, Kestutis, Nelson, Edward L, Holcombe, Randall F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283445/ https://www.ncbi.nlm.nih.gov/pubmed/22270330 http://dx.doi.org/10.1186/1475-2867-12-2 |
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