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Adoptive transfer of IL-4Rα(+ )macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation

BACKGROUND: The IL-4 receptor α (IL-4Rα) chain has a broad expression pattern and participates in IL-4 and IL-13 signaling, allowing it to influence several pathological components of allergic lung inflammation. We previously reported that IL-4Rα expression on both bone marrow-derived and non-bone m...

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Detalles Bibliográficos
Autores principales: Ford, Andrew Q, Dasgupta, Preeta, Mikhailenko, Irina, Smith, Elizabeth MP, Noben-Trauth, Nancy, Keegan, Achsah D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283450/
https://www.ncbi.nlm.nih.gov/pubmed/22292924
http://dx.doi.org/10.1186/1471-2172-13-6