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Novel immune-modulator identified by a rapid, functional screen of the parapoxvirus ovis (Orf virus) genome

BACKGROUND: The success of new sequencing technologies and informatic methods for identifying genes has made establishing gene product function a critical rate limiting step in progressing the molecular sciences. We present a method to functionally mine genomes for useful activities in vivo, using a...

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Detalles Bibliográficos
Autores principales: McGuire, Michael J, Johnston, Stephen A, Sykes, Kathryn F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283511/
https://www.ncbi.nlm.nih.gov/pubmed/22243932
http://dx.doi.org/10.1186/1477-5956-10-4