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Ocular safety of sildenafil citrate when administered chronically for pulmonary arterial hypertension: results from phase III, randomised, double masked, placebo controlled trial and open label extension

Objective To assess the ocular effects and safety profile of chronic sildenafil oral dosing in patients with pulmonary arterial hypertension. Design 12 week, double masked, randomised, placebo controlled, phase III trial with open label extension. Setting 53 institutions worldwide. Participants 277...

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Detalles Bibliográficos
Autores principales: Wirostko, Barbara M, Tressler, Charles, Hwang, Lie-Ju, Burgess, Gary, Laties, Alan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283528/
https://www.ncbi.nlm.nih.gov/pubmed/22354598
http://dx.doi.org/10.1136/bmj.e554