Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias

BACKGROUND: Moderately elevated blood levels of homocysteine are weakly correlated with coronary heart disease (CHD) risk, but causality remains uncertain. When folate levels are low, the TT genotype of the common C677T polymorphism (rs1801133) of the methylene tetrahydrofolate reductase gene (MTHFR...

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Detalles Bibliográficos
Autores principales: Clarke, Robert, Bennett, Derrick A., Parish, Sarah, Verhoef, Petra, Dötsch-Klerk, Mariska, Lathrop, Mark, Xu, Peng, Nordestgaard, Børge G., Holm, Hilma, Hopewell, Jemma C., Saleheen, Danish, Tanaka, Toshihiro, Anand, Sonia S., Chambers, John C., Kleber, Marcus E., Ouwehand, Willem H., Yamada, Yoshiji, Elbers, Clara, Peters, Bas, Stewart, Alexandre F. R., Reilly, Muredach M., Thorand, Barbara, Yusuf, Salim, Engert, James C., Assimes, Themistocles L., Kooner, Jaspal, Danesh, John, Watkins, Hugh, Samani, Nilesh J., Collins, Rory, Peto, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283559/
https://www.ncbi.nlm.nih.gov/pubmed/22363213
http://dx.doi.org/10.1371/journal.pmed.1001177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283559/
https://www.ncbi.nlm.nih.gov/pubmed/22363213
http://dx.doi.org/10.1371/journal.pmed.1001177

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