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The Formation and Stabilization of a Novel G-Quadruplex in the 5′-Flanking Region of the Relaxin Gene

It has been reported that binding of STAT3 protein to the 5′-flanking region of the relaxin gene may result in downregulation of the relaxin expression. There is a Guanine(G)-rich segment located in about 3.8 Kb upstream of the relaxin gene and very close to the STAT3's binding site. In our stu...

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Detalles Bibliográficos
Autores principales: Lin, Sen, Gu, Huiping, Xu, Ming, Cui, Xiaojie, Zhang, Youyi, Gao, Wei, Yuan, Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283602/
https://www.ncbi.nlm.nih.gov/pubmed/22363579
http://dx.doi.org/10.1371/journal.pone.0031201