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The Formation and Stabilization of a Novel G-Quadruplex in the 5′-Flanking Region of the Relaxin Gene
It has been reported that binding of STAT3 protein to the 5′-flanking region of the relaxin gene may result in downregulation of the relaxin expression. There is a Guanine(G)-rich segment located in about 3.8 Kb upstream of the relaxin gene and very close to the STAT3's binding site. In our stu...
Autores principales: | Lin, Sen, Gu, Huiping, Xu, Ming, Cui, Xiaojie, Zhang, Youyi, Gao, Wei, Yuan, Gu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283602/ https://www.ncbi.nlm.nih.gov/pubmed/22363579 http://dx.doi.org/10.1371/journal.pone.0031201 |
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