The Cerebro-Morphological Fingerprint of a Progeroid Syndrome: White Matter Changes Correlate with Neurological Symptoms in Xeroderma Pigmentosum

BACKGROUND: Xeroderma pigmentosum (XP) is a rare autosomal recessive progeroid syndrome. It has recently been shown that the underlying DNA repair defect plays a central role in the aging process. In addition to skin symptoms, various premature neurological abnormalities have been reported. METHODOL...

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Detalles Bibliográficos
Autores principales: Kassubek, Jan, Sperfeld, Anne-Dorte, Pinkhardt, Elmar H., Unrath, Alexander, Müller, Hans-Peter, Scharffetter-Kochanek, Karin, Ludolph, Albert C., Berneburg, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283603/
https://www.ncbi.nlm.nih.gov/pubmed/22363517
http://dx.doi.org/10.1371/journal.pone.0030926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283603/
https://www.ncbi.nlm.nih.gov/pubmed/22363517
http://dx.doi.org/10.1371/journal.pone.0030926

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