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Discovery of Prostamide F(2α) and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability
It was suggested that endocannabinoids are metabolized by cyclooxygenase (COX)-2 in the spinal cord of rats with kaolin/λ-carrageenan-induced knee inflammation, and that this mechanism contributes to the analgesic effects of COX-2 inhibitors in this experimental model. We report the development of a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283613/ https://www.ncbi.nlm.nih.gov/pubmed/22363560 http://dx.doi.org/10.1371/journal.pone.0031111 |