Cargando…
Discovery of Prostamide F(2α) and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability
It was suggested that endocannabinoids are metabolized by cyclooxygenase (COX)-2 in the spinal cord of rats with kaolin/λ-carrageenan-induced knee inflammation, and that this mechanism contributes to the analgesic effects of COX-2 inhibitors in this experimental model. We report the development of a...
Autores principales: | Gatta, Luisa, Piscitelli, Fabiana, Giordano, Catia, Boccella, Serena, Lichtman, Aron, Maione, Sabatino, Di Marzo, Vincenzo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283613/ https://www.ncbi.nlm.nih.gov/pubmed/22363560 http://dx.doi.org/10.1371/journal.pone.0031111 |
Ejemplares similares
-
Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection
por: Guida, Francesca, et al.
Publicado: (2012) -
The Modulation of Pain by Metabotropic Glutamate Receptors 7 and 8 in the Dorsal Striatum
por: Boccella, Serena, et al.
Publicado: (2020) -
Serotonergic Modulation of Nociceptive Circuits in Spinal Cord Dorsal Horn
por: Bardoni, Rita
Publicado: (2019) -
The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats
por: de Novellis, Vito, et al.
Publicado: (2011) -
Central expression of synaptophysin and synaptoporin in nociceptive afferent subtypes in the dorsal horn
por: Chung, Jumi, et al.
Publicado: (2019)