Cargando…

Preformed CD40L Is Stored in Th1, Th2, Th17, and T Follicular Helper Cells as Well as CD4(+)8(−) Thymocytes and Invariant NKT Cells but Not in Treg Cells

CD40L is essential for the development of adaptive immune responses. It is generally thought that CD40L expression in CD4(+) T cells is regulated transcriptionally and made from new mRNA following antigen recognition. However, imaging studies show that the majority of cognate interactions between ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Koguchi, Yoshinobu, Buenafe, Abigail C., Thauland, Timothy J., Gardell, Jennifer L., Bivins-Smith, Elizabeth R., Jacoby, David B., Slifka, Mark K., Parker, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283616/
https://www.ncbi.nlm.nih.gov/pubmed/22363608
http://dx.doi.org/10.1371/journal.pone.0031296