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Loss of the Tumor Suppressor Pten Promotes Proliferation of Drosophila melanogaster Cells In Vitro and Gives Rise to Continuous Cell Lines

In vivo analysis of Drosophila melanogaster has enhanced our understanding of many biological processes, notably the mechanisms of heredity and development. While in vivo analysis of mutants has been a strength of the field, analyzing fly cells in culture is valuable for cell biological, biochemical...

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Detalles Bibliográficos
Autores principales: Justiniano, Steven E., Mathew, Anne, Mitra, Sayan, Manivannan, Sathiya N., Simcox, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283623/
https://www.ncbi.nlm.nih.gov/pubmed/22363644
http://dx.doi.org/10.1371/journal.pone.0031417