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Probiotic Bacteria Produce Conjugated Linoleic Acid Locally in the Gut That Targets Macrophage PPAR γ to Suppress Colitis

BACKGROUND: Inflammatory bowel disease (IBD) therapies are modestly successful and associated with significant side effects. Thus, the investigation of novel approaches to prevent colitis is important. Probiotic bacteria can produce immunoregulatory metabolites in vitro such as conjugated linoleic a...

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Detalles Bibliográficos
Autores principales: Bassaganya-Riera, Josep, Viladomiu, Monica, Pedragosa, Mireia, De Simone, Claudio, Carbo, Adria, Shaykhutdinov, Rustem, Jobin, Christian, Arthur, Janelle C., Corl, Benjamin A., Vogel, Hans, Storr, Martin, Hontecillas, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283634/
https://www.ncbi.nlm.nih.gov/pubmed/22363592
http://dx.doi.org/10.1371/journal.pone.0031238