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Probiotic Bacteria Produce Conjugated Linoleic Acid Locally in the Gut That Targets Macrophage PPAR γ to Suppress Colitis
BACKGROUND: Inflammatory bowel disease (IBD) therapies are modestly successful and associated with significant side effects. Thus, the investigation of novel approaches to prevent colitis is important. Probiotic bacteria can produce immunoregulatory metabolites in vitro such as conjugated linoleic a...
Autores principales: | Bassaganya-Riera, Josep, Viladomiu, Monica, Pedragosa, Mireia, De Simone, Claudio, Carbo, Adria, Shaykhutdinov, Rustem, Jobin, Christian, Arthur, Janelle C., Corl, Benjamin A., Vogel, Hans, Storr, Martin, Hontecillas, Raquel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283634/ https://www.ncbi.nlm.nih.gov/pubmed/22363592 http://dx.doi.org/10.1371/journal.pone.0031238 |
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