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Association of Mitochondrial DNA Variations with Lung Cancer Risk in a Han Chinese Population from Southwestern China
Mitochondrial DNA (mtDNA) is particularly susceptible to oxidative damage and mutation due to the high rate of reactive oxygen species (ROS) production and limited DNA-repair capacity in mitochondrial. Previous studies demonstrated that the increased mtDNA copy number for compensation for damage, wh...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283641/ https://www.ncbi.nlm.nih.gov/pubmed/22363619 http://dx.doi.org/10.1371/journal.pone.0031322 |