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Association of Mitochondrial DNA Variations with Lung Cancer Risk in a Han Chinese Population from Southwestern China

Mitochondrial DNA (mtDNA) is particularly susceptible to oxidative damage and mutation due to the high rate of reactive oxygen species (ROS) production and limited DNA-repair capacity in mitochondrial. Previous studies demonstrated that the increased mtDNA copy number for compensation for damage, wh...

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Detalles Bibliográficos
Autores principales: Zheng, Shizhen, Qian, Pin, Li, Fuxiang, Qian, Guisheng, Wang, Changzheng, Wu, Guoming, Li, Qi, Chen, Yan, Li, Jin, Li, Haining, He, Binfeng, Ji, Fuyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283641/
https://www.ncbi.nlm.nih.gov/pubmed/22363619
http://dx.doi.org/10.1371/journal.pone.0031322