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Gis1 and Rph1 Regulate Glycerol and Acetate Metabolism in Glucose Depleted Yeast Cells

Aging in organisms as diverse as yeast, nematodes, and mammals is delayed by caloric restriction, an effect mediated by the nutrient sensing TOR, RAS/cAMP, and AKT/Sch9 pathways. The transcription factor Gis1 functions downstream of these pathways in extending the lifespan of nutrient restricted yea...

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Detalles Bibliográficos
Autores principales: Orzechowski Westholm, Jakub, Tronnersjö, Susanna, Nordberg, Niklas, Olsson, Ida, Komorowski, Jan, Ronne, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283669/
https://www.ncbi.nlm.nih.gov/pubmed/22363679
http://dx.doi.org/10.1371/journal.pone.0031577