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Gis1 and Rph1 Regulate Glycerol and Acetate Metabolism in Glucose Depleted Yeast Cells
Aging in organisms as diverse as yeast, nematodes, and mammals is delayed by caloric restriction, an effect mediated by the nutrient sensing TOR, RAS/cAMP, and AKT/Sch9 pathways. The transcription factor Gis1 functions downstream of these pathways in extending the lifespan of nutrient restricted yea...
Autores principales: | Orzechowski Westholm, Jakub, Tronnersjö, Susanna, Nordberg, Niklas, Olsson, Ida, Komorowski, Jan, Ronne, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283669/ https://www.ncbi.nlm.nih.gov/pubmed/22363679 http://dx.doi.org/10.1371/journal.pone.0031577 |
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