Drosophila as a Model for MECP2 Gain of Function in Neurons

Methyl-CpG-binding protein 2 (MECP2) is a multi-functional regulator of gene expression. In humans loss of MECP2 function causes classic Rett syndrome, but gain of MECP2 function also causes mental retardation. Although mouse models provide valuable insight into Mecp2 gain and loss of function, the...

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Detalles Bibliográficos
Autores principales: Vonhoff, Fernando, Williams, Alison, Ryglewski, Stefanie, Duch, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283685/
https://www.ncbi.nlm.nih.gov/pubmed/22363746
http://dx.doi.org/10.1371/journal.pone.0031835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283685/
https://www.ncbi.nlm.nih.gov/pubmed/22363746
http://dx.doi.org/10.1371/journal.pone.0031835

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