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Regulation of Neuronal APL-1 Expression by Cholesterol Starvation

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition of β-amyloid plaques composed primarily of the amyloid-β peptide, a cleavage product of amyloid precursor protein (APP). While mutations in APP lead to the development of Familial Alzheimer'...

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Detalles Bibliográficos
Autores principales: Wiese, Mary, Antebi, Adam, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283687/
https://www.ncbi.nlm.nih.gov/pubmed/22363792
http://dx.doi.org/10.1371/journal.pone.0032038