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Identification of CMTM7 as a Transmembrane Linker of BLNK and the B-Cell Receptor
BLNK is a pivotal adaptor protein in the signal transduction pathway from the IgM class B-cell receptor. BLNK is phosphorylated by Syk and binds various signaling intermediates, leading to cellular events including MAP-kinase activation, culminating in cellular activation. It remains unclear how BLN...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283690/ https://www.ncbi.nlm.nih.gov/pubmed/22363743 http://dx.doi.org/10.1371/journal.pone.0031829 |